Ribosomal protein S3



Ribosomal protein S3 (RPS3) is one of the 22 proteins which belong to the small subunit of the bacterial ribosome. It is known to be involved in the binding of initiator tRNA fMet. The images at the left and at the right correspond to one representative RPS3, i.e. the crystal structure of Ribosomal protein S3 from Escherichia coli (3kc4).

3D Structures of Ribosomal protein S3
Update June 2011

S3 in small ribosomal subunit
2zm6, 1n36, 1j5e, 3oto - TtRPS3 in 30S ribosomal subunit+THX+16S RRNA – Thermus thermophilus

2vqe, 2vqf, 2uuc, 2e5l, 2uu9, 2uua, 2uub, 3pyn, 3pyq, 3pys, 3pyu - TtRPS3 in 30S ribosomal subunit+16S RRNA+RNA fragment

3kc4 – EcRPS3 in 30S ribosomal subunit - Escherichia coli

3i1m, 3i1o, 3df1, 3df3, 2vho, 2vhp, 2avy, 2aw7, 1pnx - EcRPS3 in 30S ribosomal subunit+16S RRNA

1i94, 1fka - TtRPS3 in 30S ribosomal subunit+16S RRNA

1p87 - EcRPS3 in 30S ribosomal subunit+16S RRNA – Cryo-EM

3bbn - RPS3 in 30S ribosomal subunit+16S RRNA – Cryo-EM – spinach

S3 in small + large ribosomal subunit
1ml5 - EcRPS3 in 30S ribosomal subunit+50S ribosomal subunit+THX+chain release factor 2+P-site tRNA+tRNA Phe+mRNA fragment+23S RRNA+5S RRNA+16S RRNA - EM

S3 in small ribosomal subunit+ chain release factor
3mr8, 3ms0 – TtRPS3 in 30S ribosomal subunit+THX+chain release factor 1+P-site tRNA+mRNA+16S RRNA

3d5a, 3d5c - TtRPS3 in 30S ribosomal subunit+THX+chain release factor 1+P-site tRNA+E-site tRNA+mRNA +16S RRNA

2b64 - TtRPS3 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA Phe+mRNA +16S RRNA+chain release factor 1

2b9m - TtRPS3 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA Phe+mRNA +16S RRNA+chain release factor 2

2x9r, 2x9t, 2wh1, 2wh3 - TtRPS2 in 30S ribosomal subunit+THX+chain release factor 2+P-site tRNA+mRNA +16S RRNA

3f1e, 3f1g - TtRPS3 in 30S ribosomal subunit+THX+chain release factor 2+P-site tRNA+E-site tRNA +16S RRNA

S3 in small ribosomal subunit+tRNA+mRNA
2hgi - TtRPS3 in 30S ribosomal subunit+16S RRNA+tRNA Phe+tRNA fMet

2hgp, 2i2p, 2i2u - TtRPS3 in 30S ribosomal subunit+16S RRNA+tRNA Phe+mRNA

2hgr - TtRPS3 in 30S ribosomal subunit+16S RRNA+tRNA Phe+tRNA fMet+mRNA

1yl4 – TtRPS3 in 30S ribosomal subunit+ tRNA Phe+16S RRNA+THRS mRNA operator

1pns - EcRPS3 in 30S ribosomal subunit+ tRNA Phe+16S RRNA+mRNA

1xnq, 1xnr- TtRPS3 in 30S ribosomal subunit+THX+mRNA+tRNA anticodon+16S RRNA

S3 in small ribosomal subunit+A-site tRNA
2uxd, 2uxc - TtRPS3 in 30S ribosomal subunit+THX+A-site mRNA CGGG+tRNA anticodon+16S RRNA

1n32, 1n33 - TtRPS3 in 30S ribosomal subunit+THX+A-site mRNA fragment+tRNA anticodon+16S RRNA

1n34 - TtRPS3 in 30S ribosomal subunit+THX+A-site mRNA fragment +16S RRNA

1xmo, 1xmq - TtRPS3 in 30S ribosomal subunit+THX+A-site mRNA+tRNA anticodon+16S RRNA

2uxb - TtRPS3 in 30S ribosomal subunit+THX+A-site mRNA GGGU+tRNA anticodon+16S RRNA

S3 in small ribosomal subunit+P-site tRNA
3i8g - TtRPS3 in 30S ribosomal subunit+P-site tRNA+mRNA +16S RRNA

3i8h, 3i9b, 3i9d - TtRPS3 in 30S ribosomal subunit+THX+P-site tRNA+mRNA +16S RRNA

1ibk - TtRPS3 in 30S ribosomal subunit+THX+P-site mRNA fragment +16S RRNA

2wwl - EcRPS3 in 30S ribosomal subunit+Poly-Ala chain+P-site tRNA+mRNA +16S RRNA - Escherichia coli

3i1q - EcRPS3 in 30S ribosomal subunit+P-site tRNA hairpin+mRNA

3i1s, 3i1z, 3i21 - EcRPS3 in 30S ribosomal subunit+P-site tRNA hairpin+mRNA +16S RNA

S3 in small ribosomal subunit+A-site tRNA+P-site tRNA
1ibl, 1ibm - TtRPS3 in 30S ribosomal subunit+THX+A-site mRNA fragment+P-site mRNA fragment+tRNA anticodon+16S RRNA

S3 in small ribosomal subunit+P-site tRNA+E-site tRNA
2ow8 - TtRPS3 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA+mRNA +16S RRNA

2b9o - TtRPS3 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA Phe+mRNA +16S RRNA

2qnh - TtRPS3 in 30S ribosomal subunit+THX+P-site tRNA+E-site tRNA+mRNA +16S RRNA

2wdg, 2wdh, 2wdk, 2wdm - TtRPS3 in 30S ribosomal subunit+THX+P-site tRNA+E-site tRNA+mRNA +16S RRNA+tRNA Phe

S3 in small ribosomal subunit+A-site tRNA+P-site tRNA+E-site tRNA
2gy9, 2gyb - EcRPS3 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA – Cryo-EM

1jgo, 1jgp, 1jgq, 1gix - TtRPS3 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+tRNA Phe+mRNA +16S RRNA

3e1a, 3e1c - EcRPS3 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA

S3 in small ribosomal subunit + antibiotics
1i95, 1i97, 2hhh, 2f4v, 3oge, 3ogy, 3ohc, 3ohd, 3ohy, 3oi0, 3oi2, 3oi4 - TtRPS3 in 30S ribosomal subunit+16S RRNA+antibiotic

1hnw, 1hnx, 1hnz, 1fjg - TtRPS3 in 30S ribosomal subunit+16S RRNA+mRNA fragment+antibiotic

2qbb, 2qb9, 1vs5, 1vs7, 2qan, 2qal, 2qou, 2qow, 2qoy, 2qp0, 2z4k, 2z4m,3oaq, 3oar, 3ofa, 3ofb, 3ofo, 3ofp, 3ofx, 3ofy, 3or9, 3ora- EcRPS3 in 30S ribosomal subunit+16S RRNA+antibiotic

2j00, 2j02 - TtRPS3 in 30S ribosomal subunit+16S RRNA+paromomycin+P-site tRNA fMet+E-site tRNA Phe+mRNA

3knj, 3knh - TtRPS3 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA+viomycin

3knl, 3knm, 3knn, 3kno - TtRPS3 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA+capreomycin

S3 in small ribosomal subunit + ribosome recycling factor
2qbd, 2qbf - EcRPS3 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor

3r8n, 3r8o – EcRPS3 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor + mRNA + tRNA

2qbh, 2qbj - EcRPS3 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor+gentamicin

2v46, 2v48 - TtRPS3 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor+P-site tRNA Phe+mRNA+tRNA fMet

S3 in small ribosomal subunit + elongation factor
2wri, 2wrk - TtRPS3 in 30S ribosomal subunit+THX+P-site tRNA+mRNA +16S RRNA+elongation factor G

2wrn, 2wrq - TtRPS3 in 30S ribosomal subunit+THX+A-site tRNA+mRNA +16S RRNA+elongation factor TU-4

3fic - TtRPS3 in 30S ribosomal subunit+THX+A-site tRNA+P-site tRNA+E-site tRNA+mRNA codon+16S RRNA+elongation factor TU-A

2y0u, 2y0w, 2y0y, 2y10, 2y12, 2y14, 2y16, 2y18 - TtRPS2 in 30S subunit+THX+A-site tRNA+E-site tRNA+mRNA codon+16S RRNA+elongation factor TU

3fih - EcRPS3 in 30S ribosomal subunit+A-site tRNA Phe+P-site tRNA+mRNA +16S RRNA+elongation factor TU

3izv – EcRPS3 in 30S ribosomal subunit+A/T-site tRNA Phe +16S RRNA+elongation factor TU

3izw – EcRPS3 in 30S ribosomal subunit+A-site tRNA Phe +mRNA +16S RRNA+elongation factor TU

3huw, 3huy - TtRPS3 in 30S ribosomal subunit+THX+tRNA-Met+mRNA +16S RRNA+elongation factor P

1s1h - RPS3 in 40S ribosomal subunit+18S RRNA+elongation factor 2 – Cryo-EM – yeast

S3 in small ribosomal subunit + translation initiation factor
1i96 - TtRPS3 in 30S ribosomal subunit+THX+IF3+16S RRNA

1hr0 - TtRPS3 in 30S ribosomal subunit+THX+IF+16S RRNA

S3 in small ribosomal subunit + various proteins
3kiq, 3kis, 3kiu, 3kix - TtRPS3 in 30S ribosomal subunit+toxin RelE+16S RRNA

1voq, 1vos, 1vov, 1vox, 1voz - EcRPS3 in 30S ribosomal subunit+protein Y+16S RRNA

3j00 – EcRPS3 + 16S RRNA + FTSQ + apolipoprotein A-I

S3 in small 40S ribosomal subunit + various proteins
3jyv - TlRPS3 in 40S ribosomal subunit+RACK1+S19E+P-site tRNA – Thermomyces lanuginosus

2xzm, 2xzn - RPS2 in 40S subunit+RACK1 - Tetrahymena thermophila

3o2z, 3o30 – yRPS3 in 40S ribosomal subunit+ RACK1

3iz6 – RPS3 in 40S ribosomal subunit+RACK1 - wheat